Organised by SHC

The Science of HBV Cure Meeting 2026 LIVE

For Scientists, Clinician Scientists and
Pharmacists and Industry Experts

4 – 5 September 2026

8.30am – 6.00pm SGT

The Science of HBV Cure Meeting 2026 LIVE

4 – 5 September 2026

8.30am – 6.00pm SGT

Register for Live Meeting

By registering for The Science of HBV Cure Meeting 2026, you are automatically enrolled for the SHC 2026 Online Meeting.

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Who Should Attend?

The Science of HBV Cure Meeting is important for patients, doctors, scientists and pharmaceutical companies seeking to understand Hepatitis B and its new treatments. In particular, Hepatitis B cure is becoming a reality with new drugs tested in phase 3 clinical trials.

Additionally, Hepatitis D is also emerging as a disease for which therapy is rapidly evolving.   The Science of HBV Cure Meeting will also discuss the emerging treatments for HDV.

The Science of HBV Cure Meeting 2026 LIVE Scientific Programme

Speakers names will be added soon.

September, 2026

4

Programme Time (SGT)
Welcome Remarks by the Conference Chairman 08:30 – 08:35
Opening Symposium: Overview of HBV Functional Cure
Moderators: Prof. Fabien Zoulim View Bio Prof. Jinlin Hou
HBV Cure: HBV Cure States from the Asian Consensus Conference
– Prof. Seng Gee Lim, National University Health System, Singapore View Bio
08:35 – 09:00
Challenges to achieve functional cure
Adj. Prof. Veronica Miller, UC Berkeley, Public Health, USA View Bio
09:00 – 09:20
Landscape of functional cure 2026 after Bepirovirsen phase 3 results
– Prof. Fabien Zoulim, Universite Claude Bernard Lyon 1, France View Bio
09:20 – 09:45
Q&A 09:45 – 10:00
Opening Symposium: Overview of HBV Functional Cure
Moderators: Prof. Fabien Zoulim View Bio Prof. Jinlin Hou
Free paper: Clinically meaningful functional cure rates in virologically suppressed
Chinese patients with chronic hepatitis B virus infection treated with bepirovirsen:
A subanalysis of the B-Well Phase 3 trials,
Prof. Jin Lin Hou, Nanfang University, Guangzhou, China
10:00 – 10.15
Free paper: Projected impact of hepatitis B virus functional cure therapies on
liver disease burden in China: A modelling analysis,
Dr. Devin Razavi-Shearer
10:15 – 10.30
Free paper: Metabolic Dysfunction and Its Impact on Chronic Hepatitis B
Progression Hepatitis B Functional Cure: Real-World Clinical Perspectives,
Dr. Preeti, Agarwal
10.30 – 10:45
Q&A 10.45 – 11:00
Tea Break 11:00 – 11:15
Virological Insights into functional cure
Moderators: Prof. Thomas View Bio
Virological Cure and complete cure: achievable or imaginary?
– Prof. Massimo Levrero, Universite Claude Bernard Lyon 1, France View Bio
11:15 – 11:35
Integrated HBV: what’s important? Burden, integration site or clonal expansion
– Prof. Thomas Tu, Westmead Institute for Medical Research, Australia View Bio
11:35 – 11:55
Free paper : Intrahepatic viral integration more than reservoir size dictates the HBsAg loss trajectory in Chronic Hepatitis B,
Dr. Cameron Soulette
11:55 – 12:10
Q&A 12:10 – 12:20
Lunch 12:20 – 13:00
Poster Presentation 13:00 – 13:45
Intrahepatic microenvironment
Moderator: Prof. Massimo Levrero View Bio
Spatial transcriptomics: state of the Science and Art
– Charting the Spatial Whole Transcriptome and Multiomic Frontier for Complete Biology
Dr. Prajan Divakar, Bruker Corporation
13:45 – 14:05
Spatial proteomics:
Advancements in cyclic immunofluorescence methods for liver tissue imaging and
spatial profiling enabled by the CellScape XR platform.
Dr. Benton Berigan, Bruker Corporation
14:05 – 14:25
Spatial Transcriptomics in HBV
– Prof. Jane McKeating, Oxford
14:25 – 14:50
Intrahepatic immune correlates of functional cure
– Prof. Adam Gehring, University of Toronto, Canada View Bio
14:50 – 15:10
Free paper: Spatial Transcriptomics of CHB and HBsAg loss using CosMx,
Dr. Aravind Sivakumar et al
15:10 – 15:25
Q&A 15:25 – 15:40
Tea Break 15:40 – 16:00
Animal Models
Moderator: Prof. Qingfeng Chen View Bio
Benefits and limitations of animal models to assess antivirals and
immune modulators for Functional Cure.
Prof. Maura Dandri, University Medical Center Hamburg-Eppendorf Germany View Bio
16:00 – 16:20
Free paper: Impact of Bulevirtide on Hepatocyte Transcriptional Programs
in a Humanized Mouse Model of HDV Infection.
Dr. Wakae Kousho (abstract 48)
16:20 – 16:35
Q&A 16:35 – 16:45
Delta Cure
Moderator: Prof. Pietro Lampertico View Bio
Delta Cure update
– Prof. Heiner Wedemeyer, Hannover Medical School, Germany View Bio
16:45 – 17:05
Novel therapeutics for Delta Cure
Prof. Pietro Lampertico, Italy View Bio
17:05 – 17:25
Q&A 17:25 – 17:35
End of day 1 17:35

September, 2026

5

Programme Time (SGT)
Biomarkers
Moderators: Prof. Teerha Piratvisuth View Bio
HBsAg levels in real world and for clinical trials of novel therapies
– Prof. Man-Fung Yuen, Hong Kong View Bio
08:30 – 08:50
Biomarkers that corelate with cccDNA
– Prof. Jordan Feld, University of Toronto, Canada View Bio
08:50 – 09:10
Using Biomarkers for management of CHB with novel therapies
– Prof. Yasuhito Tanaka, Kumamoto University View Bio
09:10 – 09:30
Q&A 09:30 – 09:40
RNA interference
Moderators: Prof. Mala Maini View Bio
Anti-sense oligonucleotides: are they immune modulators?
– Prof. Antonio Bertoletti, Duke NUS Graduate School of Medicine, Singapore View Bio
09 40 – 10:00
The role of siRNA in HBV cure therapies
– Prof. MF Yuen, Hong Kong University, Hong Kong View Bio
10:00 – 10:20
Q&A 10:20– 10:30
Tea Break 10:30 – 10:45
Poster Presentation 10:45 – 11:00
Strategies with existing agents
Moderator: Prof. Seng Gee Lim View Bio
Stopping nucleoside analogues: is there still a role in FC?
– Prof. Seng Gee Lim, National University Health System, Singapore View Bio
11:00 – 11:20
Peginterferon: never say die
– Prof. Teerha Piratsuvith, Prince of Songkla University, Thailand View Bio
11:20 – 11:40
Free paper To Stop or Not to Stop? End-of-Treatment HBcrAg for Predicting
Relapse After Nucleos(t)ide Analogue Cessation in Chronic Hepatitis B: A
Diagnostic Test Accuracy Meta-Analysis. Budiman et al (abstract 35)
11:40 – 11:55
Q&A 11:55 – 12:10
Lunch 12:10 – 13:10
Invited Pharma Presentations
Moderators: Prof. Lim Seng Gee View Bio and Prof. Adam Gehring View Bio
Bepirovirsen: The Journey So Far
Attila Mihalyi (Vice President, Global Medical Lead, Hepatitis B)
GSK
13:10 – 13:25
AHB-137, update
Dr. Guo Feng Cheng, CEO, Ausperbio Therapeutics Inc
13:25 – 13:40
siRNA+Neutralizing antibody
– Dr. Wu Kai, CEO, Hepa Thera Biopharmaceutical Co., Ltd
13:40 – 13:55
VRON-0200: Priming Immunity for CHB Cure: A Clinical Update
Dr. Sue Currie, COO, Virion Therapeutics LLC
13:55 – 14:10
Q&A 14:10 – 14:20
Immunology
Moderator: Prof. Antonio Bertoletti View Bio
The challenges and promise of immune modulation for FC
– Prof. Mala Maini, University College London, UK View Bio
14:20 – 14:40
Antibody therapeutics in the quest for Functional Cure
– Prof. Adam Gehring, University of Toronto, Canada View Bio
14:40 – 15:00
Free paper: Characterisation and discovery of epitopes of anti-HBe during HBeAg seroconversion,
Dr. Low Heng Boon et al
15:00 – 15:15
Free paper: Peg-interferon modulates the trajectory of peripheral immunity in
functionally cured chronic hepatitis B patients, Neo et al (abstract 26)
15:15 – 15:30
Free paper: First-in-Human Safety of the Dendritic Cell–Targeting
Immunotherapy SN2001 with Translational Evidence Supporting Restoration of
HBV-Specific Cellular Immunity, Shi et al (abstract 50)
15:30 – 15:45
Q&A 15:45 – 16:00
Tea Break 16:00 – 16:15
Gene Therapy
Moderators: Prof. Fabien Zoulim View Bio
Early clinical results of gene/epigenetic editing
– Prof. Ed Gane, University of Auckland, New Zealand View Bio
16:15 – 16:35
The safety of gene editing: What to measure and for how long?
– Dr. Wei Leong Chew GIS, ASTAR View Bio
16:35 – 16:55
Q&A 16:55 – 17:10
Closing remarks from Chairman 17:10 – 17.15

Call for Abstracts

Submission Deadline: 7 July 2026

We invite all interested parties to present their research papers. (abstracts of Case Studies will not be accepted) Click on below Abstracts and Posters for further information.

Abstracts will be reviewed by the Abstract Selection Committee and accepted submissions will be posted on Abstract & Poster Gallery in our website and in the Poster Hall. Presenters of oral presentations of accepted Abstracts as Free Papers will receive USD800 and a registration fee refund to help defray the cost of travel and accommodation here in Singapore.  This payment will be made after the presentation.

Only abstracts of research papers will be accepted. Abstracts of Case Studies will not be accepted.